Kazuma Yamakawa Selected Research

Dacarbazine (DIC)

6/2022	Prognostic value of serum high mobility group box 1 protein and histone H3 levels in patients with disseminated intravascular coagulation: a multicenter prospective cohort study.
6/2022	Special Issue on "Disseminated Intravascular Coagulation: Current Understanding and Future Perspectives".
1/2022	Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis.
1/2021	Recombinant Thrombomodulin in Disseminated Intravascular Coagulation Associated with Stage IV Solid Tumors: A Nationwide Observational Study in Japan.
1/2021	Age Is Associated With the Efficacy of Anticoagulant Therapies Against Sepsis-Induced Disseminated Intravascular Coagulation.
1/2021	Pathophysiology of Coagulopathy Induced by Traumatic Brain Injury Is Identical to That of Disseminated Intravascular Coagulation With Hyperfibrinolysis.
1/2021	Disseminated intravascular coagulation immediately after trauma predicts a poor prognosis in severely injured patients.
10/2020	Time Trends of the Outcomes and Treatment Options for Disseminated Intravascular Coagulation: A Nationwide Observational Study in Japan.
10/2020	Underlying Disorders, Clinical Phenotypes, and Treatment Diversity among Patients with Disseminated Intravascular Coagulation.
9/2020	Antithrombin use and mortality in patients with stage IV solid tumor-associated disseminated intravascular coagulation: a nationwide observational study in Japan.

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Kazuma Yamakawa Research Topics

Disease

63	Sepsis (Septicemia) 01/2022 - 01/2011
41	Disseminated Intravascular Coagulation 06/2022 - 01/2011
17	Wounds and Injuries (Trauma) 11/2021 - 05/2011
15	Septic Shock (Toxic Shock Syndrome) 08/2021 - 01/2016
13	Thrombosis (Thrombus) 06/2022 - 01/2011
13	Hemorrhage 11/2021 - 04/2013
8	Infections 01/2022 - 11/2011
8	Critical Illness (Critically Ill) 01/2021 - 06/2015
7	Inflammation (Inflammations) 01/2021 - 06/2012
6	COVID-19 01/2022 - 09/2020
4	Pneumonia (Pneumonitis) 01/2022 - 05/2011
4	Neoplasms (Cancer) 01/2021 - 09/2020
4	Multiple Organ Failure (MODS) 01/2021 - 06/2012
3	Ventilator-Associated Pneumonia 01/2022 - 01/2017
2	Communicable Diseases (Infectious Diseases) 01/2022 - 01/2017
2	Muscular Diseases (Myopathy) 01/2021 - 01/2020
2	Leukemia 10/2020 - 10/2020
2	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2017 - 07/2015
2	Crush Injuries 12/2016 - 06/2012
1	Gram-Negative Bacterial Infections 12/2021
1	Bacteriuria 12/2021
1	Seizures (Absence Seizure) 11/2021
1	Hyperglycemia 10/2021
1	Frailty 08/2021
1	Acute Liver Failure (Fulminant Hepatic Failure) 07/2021
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 07/2021
1	Lung Injury 07/2021
1	Burns 01/2021
1	Exsanguination 01/2021
1	Shock 01/2021
1	Pancreatitis 10/2020
1	Aortic Diseases 10/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 09/2020
1	Diabetes Mellitus 01/2020

Drug/Important Bio-Agent (IBA)

40	Dacarbazine (DIC)FDA LinkGeneric 06/2022 - 01/2011
15	AnticoagulantsIBA 01/2022 - 01/2011
14	ThrombomodulinIBA 01/2022 - 01/2011
11	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2013
10	AntithrombinsIBA 01/2022 - 01/2016
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 11/2011
4	Fibrinogen (Factor I)FDA Link 03/2021 - 02/2019
3	Coloring Agents (Dyes)IBA 01/2022 - 01/2017
3	Oxygen (Dioxygen)IBA 01/2022 - 01/2021
3	Tranexamic Acid (AMCA)FDA Link 11/2021 - 01/2017
3	fibrin fragment D (D-dimer)IBA 01/2021 - 02/2019
2	Histones (Histone)IBA 06/2022 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 06/2022 - 06/2012
2	HMGB1 Protein (HMG1)IBA 06/2022 - 06/2012
2	FibrinIBA 06/2022 - 09/2020
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2021
2	ConnectinIBA 01/2021 - 01/2020
2	remdesivirIBA 01/2021 - 01/2021
2	favipiravirIBA 01/2021 - 01/2021
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2021
2	tocilizumab (atlizumab)FDA Link 01/2021 - 01/2021
2	Polymyxin B (Aerosporin)FDA LinkGeneric 11/2020 - 04/2017
2	EndotoxinsIBA 11/2020 - 06/2013
2	Hemostatics (Antihemorrhagics)IBA 09/2020 - 03/2016
2	Plasminogen Activators (Plasminogen Activator)IBA 09/2020 - 01/2020
2	SteroidsIBA 01/2020 - 11/2011
2	Heparin (Liquaemin)FDA LinkGeneric 11/2019 - 01/2016
2	ProcalcitoninIBA 01/2019 - 01/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 06/2012
2	Receptor for Advanced Glycation End ProductsIBA 01/2017 - 06/2012
1	SuspensionsIBA 01/2022
1	beta-Lactamases (beta-Lactamase)IBA 12/2021
1	Indicators and Reagents (Reagents)IBA 12/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2021
1	nintedanibIBA 07/2021
1	Immunoglobulin Fab FragmentsIBA 01/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021
1	formycin diphosphate (FDP)IBA 01/2021
1	salicylhydroxamic acid (SHAM)IBA 01/2021
1	baricitinibIBA 01/2021
1	CatecholaminesIBA 01/2021
1	Vasopressins (Vasopressin)IBA 01/2021
1	casirivimab and imdevimab drug combinationIBA 01/2021
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2021
1	antithrombin III-protease complexIBA 09/2020
1	plasmin-plasmin inhibitor complexIBA 09/2020
1	Amino Acids FDA Link 01/2020
1	Blood Glucose (Blood Sugar)IBA 01/2020

Therapy/Procedure

28	Therapeutics 01/2022 - 01/2011
10	Critical Care (Surgical Intensive Care) 08/2021 - 05/2011
8	Resuscitation 01/2021 - 01/2017
5	Mechanical Ventilators (Ventilator) 01/2021 - 05/2012
3	Artificial Respiration (Mechanical Ventilation) 01/2022 - 01/2021
3	Length of Stay 08/2021 - 10/2020
2	Patient Care Bundles 01/2022 - 11/2019
2	Hemoperfusion 11/2020 - 04/2017
2	Patient Transfer (Patient Dumping) 01/2019 - 01/2018
2	Intravenous Administration 01/2017 - 06/2012
1	Punctures 01/2022
1	Nutrition Therapy (Medical Nutrition Therapy) 01/2022
1	Intraperitoneal Injections 01/2022
1	Ligation 01/2022
1	Glycemic Control 10/2021
1	Blood Transfusion (Blood Transfusions) 03/2021
1	Cell Transplantation 01/2021
1	Transplantation 01/2021